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TIRA:用空间免疫拓扑实现零样本跨癌种MSI与TMB预测
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研究者提出 TIRA(Tumor Immune Representation Adaptation),这是一个免目标域数据的框架,通过对冻结的病理基础模型表征进行空间免疫拓扑微调,实现对 MSI 与 TMB 的联合预测。该方法以零样本方式跨癌种迁移,无需目标癌种的标注数据即可完成生物标志物预测。相关成果以预印本形式发表于 arXiv,归属 Computer Vision 类别,为一手研究报道。目前公开信息仅涉及方法框架本身,尚无独立验证或同行评议结果。
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Oct 8, 2026
- arXiv · Computer VisionTIRA:用肿瘤免疫表征适配实现零样本跨癌种 MSI 与 TMB 预测
研究者提出 TIRA(Tumor Immune Representation Adaptation),一个免目标域数据的框架,用空间免疫拓扑微调冻结的病理基础模型表征,联合预测 MSI 与 TMB。
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